Myrurgia was founded in 1916 by the Catalan family of Monegal. Raymon Monegal, a wealthy chemical industrialist, put up the money and marketing skills. His second son, Esteve Monegal Prat, a sculptor, art student and friend of many in the contemporary art scene, was the face of Myrurgia. Esteve was also influential in the management of the company until his death in 1978.  

While Raymon Monegal's education came from trade school and in-house training, Esteve's education came from schooling in both Barcelona and Paris. The thir generation of the family gained university degrees and received perfumery training in Grasse, in Paris, and with Firmenich in Geneva. It was Raymon Monegal's son-in-law who took over the direction of the company until his death in the 1970's. Perhaps Myrurgia's best known fragrance was Maja, first introduced in 1918 and reintroduced in 1945. After the Spanish Civil War, in the 1950's and 1960's,

​Myrurgia was Spain's leading perfumer house with Perfumeria Gal Madrid being their chief competitor. In July, 2000, Myrurgia became part of the Puig Beauty & Fashion Group.